Using MEST-C Scores and the International Study of Kidney Disease in Children Classification to Predict Outcomes of Henoch–Schönlein Purpura Nephritis in Children

Autor: Meiqiu Wang, Ren Wang, Xu He, Pei Zhang, Qianhuining Kuang, Jun Yao, Xiang Fang, Zhuo Shi, Heyan Wu, Yingchao Peng, Zhengkun Xia, Chunlin Gao
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Frontiers in Pediatrics, Vol 9 (2021)
Druh dokumentu: article
ISSN: 2296-2360
DOI: 10.3389/fped.2021.658845
Popis: Introduction: Henoch–Schönlein purpura nephritis (HSPN) and IgA nephropathy (IgAN) bear similarities in some aspects. The histological classification of HSPN was built on the International Study of Kidney Disease in Children (ISKDC) criteria, while IgAN was established on the 2016 Oxford classification (MEST-C scores). The purpose of this paper was to discuss the predictive value of the ISKDC classification and MEST-C scores in children with HSPN.Methods: We performed a retrospective study of 877 children with HSPN in a single center between 2001 and 2019. The primary outcome was defined as chronic kidney disease—estimated glomerular filtration rate (eGFR)
Databáze: Directory of Open Access Journals