| Autor: |
Seung-Chul Choi, Anton A. Titov, Georges Abboud, Howard R. Seay, Todd M. Brusko, Derry C. Roopenian, Shahram Salek-Ardakani, Laurence Morel |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-018-06686-0 |
| Popis: |
T cell functions depend on distinct metabolic fluxes. Here the authors show different metabolic requirements of humoral responses to self versus microbial antigens: while glucose is dispensable for antiviral Tfh and antibody responses, it is essential to mount these responses against autoantigens. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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