Long-Term Intravenous Ketamine for Analgesia in a Child with Severe Chronic Intestinal Graft versus Host Disease
| Autor: | Jennifer Busse, Leroy Phillips, William Schechter |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Case Reports in Anesthesiology, Vol 2015 (2015) |
| Druh dokumentu: | article |
| ISSN: | 2090-6382 2090-6390 |
| DOI: | 10.1155/2015/834168 |
| Popis: | Ketamine is reported to be an effective adjuvant to opioids in the treatment of refractory cancer pain; however, the use of high doses of ketamine for extended periods in pediatric patients has not been described. We present a five-year-old male with grade IV intestinal GVHD whose abdominal pain required both hydromorphone and ketamine for a period of over four months. There was no evidence of hepatotoxicity, hemorrhagic cystitis, or other adverse effects. Possible withdrawal symptoms were mild and were readily mitigated by gradually weaning ketamine. |
| Databáze: | Directory of Open Access Journals |
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