Role of Adipocyte Tissue Invasion as a Prognostic Marker in Invasive Breast Carcinoma - A Cross-Sectional Study

Autor: Amita K, Prajwala Nagaraju, Sunil BK, Sanjay M
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Online Journal of Health & Allied Sciences, Vol 23, Iss 1 (2024)
Druh dokumentu: article
ISSN: 0972-5997
Popis: Background: Functional lymphatics at the peritumoral site is mainly responsible for lymphovascular invasion (LVI) in breast cancer. Marginal adipose tissue invasion (ATI) leads to larger area of contact between peritumoral lymphatics and may increase chances of LVI. Objectives: To investigate whether ATI of cancer cells at the tumour margin influenced lymph node status and prognosis in patients with invasive ductal carcinoma of the breast. Materials and methods: Cross sectional study involving 33 cases of invasive ductal carcinoma diagnosed over a duration of three years. Clinicopathologic prognostic parameters in 33 cases with marginal ATI was were compared 10 patients without ATI. The value of the combination of ATI and peritumoral lymphatic vessel invasion (LVI) was also assessed. Chi square was applied to assess the statistical significance at p
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