| Autor: |
Céline Dubath, Mehdi Gholam-Rezaee, Jennifer Sjaarda, Axel Levier, Nuria Saigi-Morgui, Aurélie Delacrétaz, Anaïs Glatard, Radoslaw Panczak, Christoph U. Correll, Alessandra Solida, Kerstin Jessica Plessen, Armin von Gunten, Zoltan Kutalik, Philippe Conus, Chin B. Eap |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Translational Psychiatry, Vol 11, Iss 1, Pp 1-7 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2158-3188 |
| DOI: |
10.1038/s41398-021-01482-9 |
| Popis: |
Abstract Weight gain and metabolic complications are major adverse effects of many psychotropic drugs. We aimed to understand how socio-economic status (SES), defined as the Swiss socio-economic position (SSEP), is associated with cardiometabolic parameters after initiation of psychotropic medications known to induce weight gain. Cardiometabolic parameters were collected in two Swiss cohorts following the prescription of psychotropic medications. The SSEP integrated neighborhood-based income, education, occupation, and housing condition. The results were then validated in an independent replication sample (UKBiobank), using educational attainment (EA) as a proxy for SES. Adult patients with a low SSEP had a higher risk of developing metabolic syndrome over one year versus patients with a high SSEP (Hazard ratio (95% CI) = 3.1 (1.5–6.5), n = 366). During the first 6 months of follow-up, a significant negative association between SSEP and body mass index (BMI), weight change, and waist circumference change was observed (25 ≤ age |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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