On the application of knoevenagel condensation for the synthesis of benzylidene benzothiazine compounds and structural study

Autor: Ana Maria Alves de Souza, Vera Lucia de Miranda Guarda, Lúcia Fernanda Cavalcanti da Costa Leite, José Maria Barbosa Filho, Maria do Carmo Alves de Lima, Suely Lins Galdino, Ivan da Rocha Pitta
Jazyk: English<br />Spanish; Castilian<br />Portuguese
Rok vydání: 2006
Předmět:
Zdroj: Química Nova, Vol 29, Iss 5, Pp 1106-1109 (2006)
Druh dokumentu: article
ISSN: 1678-7064
0100-4042
DOI: 10.1590/S0100-40422006000500035
Popis: The synthesis and physico-chemical properties of new 6-acetylamino or 6-benzoyl-amino 2-benzylidene-4-methyl-4H-benzo[1,4]thiazin-3-ones and 6-benzoylamino or 6-nitro 2-benzylidene-4H-benzo[1,4]thiazin-3-ones are described. These benzylidene benzothiazine compounds were prepared by the Knoevenagel condensation with benzaldehydes. The configurations and conformations of benzylidene benzothiazine derivatives were optimised using the semi-empirical method AM1.
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