Plant–necrotroph co-transcriptome networks illuminate a metabolic battlefield

Autor: Wei Zhang, Jason A Corwin, Daniel Harrison Copeland, Julie Feusier, Robert Eshbaugh, David E Cook, Suzi Atwell, Daniel J Kliebenstein
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: eLife, Vol 8 (2019)
Druh dokumentu: article
ISSN: 2050-084X
DOI: 10.7554/eLife.44279
Popis: A central goal of studying host-pathogen interaction is to understand how host and pathogen manipulate each other to promote their own fitness in a pathosystem. Co-transcriptomic approaches can simultaneously analyze dual transcriptomes during infection and provide a systematic map of the cross-kingdom communication between two species. Here we used the Arabidopsis-B. cinerea pathosystem to test how plant host and fungal pathogen interact at the transcriptomic level. We assessed the impact of genetic diversity in pathogen and host by utilization of a collection of 96 isolates infection on Arabidopsis wild-type and two mutants with jasmonate or salicylic acid compromised immunities. We identified ten B. cinereagene co-expression networks (GCNs) that encode known or novel virulence mechanisms. Construction of a dual interaction network by combining four host- and ten pathogen-GCNs revealed potential connections between the fungal and plant GCNs. These co-transcriptome data shed lights on the potential mechanisms underlying host-pathogen interaction.
Databáze: Directory of Open Access Journals