Optimal stereotactic body radiotherapy dosage for hepatocellular carcinoma: a multicenter study

Autor: Ting-Shi Su, Qiu-Hua Liu, Xiao-Fei Zhu, Ping Liang, Shi-Xiong Liang, Lin Lai, Ying Zhou, Yong Huang, Tao Cheng, Le-Qun Li
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Radiation Oncology, Vol 16, Iss 1, Pp 1-9 (2021)
Druh dokumentu: article
ISSN: 1748-717X
DOI: 10.1186/s13014-021-01778-6
Popis: Abstract Background The optimal dose and fractionation scheme of stereotactic body radiation therapy (SBRT) for hepatocellular carcinoma (HCC) remains unclear due to different tolerated liver volumes and degrees of cirrhosis. In this study, we aimed to verify the dose-survival relationship to optimize dose selection for treatment of HCC. Methods This multicenter retrospective study included 602 patients with HCC, treated with SBRT between January 2011 and March 2017. The SBRT dosage was classified into high dose, moderate dose, and low dose levels: SaRT (BED10 ≥ 100 Gy), SbRT (EQD2 > 74 Gy to BED10
Databáze: Directory of Open Access Journals