A novel zoonotic Anaplasma species is prevalent in small ruminants: potential public health implications

Autor: Jifei Yang, Zhijie Liu, Qingli Niu, Junlong Liu, Rong Han, Guiquan Guan, Muhammad Adeel Hassan, Guangyuan Liu, Jianxun Luo, Hong Yin
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Parasites & Vectors, Vol 10, Iss 1, Pp 1-6 (2017)
Druh dokumentu: article
ISSN: 1756-3305
DOI: 10.1186/s13071-017-2182-9
Popis: Abstract Background Tick-borne diseases currently represent an important issue for global health. A number of emerging tick-transmitted microbes continue to be discovered, and some of these are already identified as the cause of human infections. Over the past two decades, Anaplasma phagocytophilum is considered to be mainly responsible for human anaplasmosis. However, a novel zoonotic pathogen provisionally named “Anaplasma capra” has recently been identified in China. In this study, we did an active surveillance of A. capra in goats and sheep in different geographical regions of China. Methods The presence of A. capra was determined by nested PCR in 547 blood samples collected from goats and sheep from 24 counties distributed in 12 provinces in China. The molecular characterization of A. capra isolates in sheep and goats was achieved based on four conventional genetic markers (16S rRNA, gltA, groEL and msp4 genes). Results Anaplasma capra was identified in 75 of 547 animals, with an overall prevalence of 13.7%. The infection rates in the survey sites ranged from 0 to 78.6%, and were significantly different (P
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