| Autor: |
R. Balasubramanian, Sreelekshmy Mohandas, Ullas P. Thankappan, Anita Shete, Dilip Patil, Kannan Sabarinath, Basavaraj Mathapati, Rima Sahay, Deepak Patil, Pragya D. Yadav |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Frontiers in Microbiology, Vol 15 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1664-302X |
| DOI: |
10.3389/fmicb.2024.1342170 |
| Popis: |
IntroductionSince 2018, the Indian state of Kerala has reported four Nipah virus (NiV) disease outbreaks, raising concerns about NiV spillover from bats to the human population. Considering this, a cross-sectional study was undertaken in the Pteropus medius bat population around the Nipah virus-affected regions of Kozhikode, Kerala, India, during February, July, and September 2023.MethodsThroat swabs, rectal swabs, and organ samples were collected from bats to test for NiV using the real-time reverse transcriptase polymerase chain reaction (RT-PCR), while serum samples were screened for anti-Nipah IgG antibodies through ELISA.ResultsAn overall seroprevalence of 20.9% was observed in 272 P. medius bats tested. The throat and rectal swab samples of 321 bats were negative for NiV RNA. However, 4 of 44 P. medius bats tested positive for NiV in their liver/spleen samples. The partial N gene retrieved showed more than 99% similarity with the earlier reported NiV genome from Kerala state, India.DiscussionThe findings of the study caution that there is a spillover risk in the region and necessary precautions should be taken. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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