Comparative Survival Outcomes of High-risk Prostate Cancer Treated with Radical Prostatectomy or Definitive Radiotherapy Regimens

Autor: Kirsti Aas, Viktor Berge, Tor Åge Myklebust, Sophie Dorothea Fosså
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: European Urology Open Science, Vol 26, Iss , Pp 55-63 (2021)
Druh dokumentu: article
ISSN: 2666-1683
DOI: 10.1016/j.euros.2021.01.011
Popis: Background: Observational data has indicated improved survival after radical prostatectomy (RP) compared with definitive radiotherapy (RT) in men with high-risk prostate cancer (PCa). Objective: To compare PCa-specific mortality (PCSM) and overall mortality (OM) in men with high-risk PCa treated with RP or RT, providing information on target doses and fractionations. Design, setting, and participants: This is an observational study from the Cancer Registry of Norway. Patients were diagnosed with high-risk PCa during 2006–2015, treated with RP ≤12 mo or RT ≤15 mo after diagnosis, and stratified according to RP or RT modality; external beam radiotherapy (EBRT; 70–
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