Thromboembolic events and haematological diseases: a case of stroke as clinical onset of a paroxysmal nocturnal haemoglobinuria

Autor: Viggiano Vito, Castaldo Giampiero, Bonamassa Barbara, Di Micco Pierpaolo, Izzo Tiziana, Granata Gianluca, Picillo Ugo, Castaldo Giuseppe, Niglio Alferio
Jazyk: angličtina
Rok vydání: 2004
Předmět:
Zdroj: Thrombosis Journal, Vol 2, Iss 1, p 10 (2004)
Druh dokumentu: article
ISSN: 1477-9560
DOI: 10.1186/1477-9560-2-10
Popis: Abstract Some haematological diseases are associated to an increased risk of thromboembolic events. We report a case of paroxysmal nocturnal haemoglobinuria (PNH) in which a cerebrovascular event represented the first clinical manifestation of disease. PNH is associated to thromboembolic events, generally of venous districts often involving unusual locations such as mesenteric vessels, sagittal veins, inferior vena cava and renal veins. To our knowledge arterial thrombotic episodes are rare and the involvement of arterial cerebral vessels is exceptional. Then, our case points out the importance of investigating about haematological disorders in all patients presenting with a stroke, in which the common predisposing conditions are excluded.
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