Neurohormonal Modulation as a Therapeutic Target in Pulmonary Hypertension

Autor:	Inés García-Lunar, Daniel Pereda, Borja Ibanez, Ana García-Álvarez
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	adrenoceptor signaling sympathetic regulation pulmonary hypertension animal models denervation Cytology QH573-671
Zdroj:	Cells, Vol 9, Iss 11, p 2521 (2020)
Druh dokumentu:	article
ISSN:	2073-4409
DOI:	10.3390/cells9112521
Popis:	The autonomic nervous system (ANS) and renin-angiotensin-aldosterone system (RAAS) are involved in many cardiovascular disorders, including pulmonary hypertension (PH). The current review focuses on the role of the ANS and RAAS activation in PH and updated evidence of potential therapies targeting both systems in this condition, particularly in Groups 1 and 2. State of the art knowledge in preclinical and clinical use of pharmacologic drugs (beta-blockers, beta-three adrenoceptor agonists, or renin-angiotensin-aldosterone signaling drugs) and invasive procedures, such as pulmonary artery denervation, is provided.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/cc3d5e17358d4622a98bc0196d0bc8d2 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.