The Effects of Hydroalcoholic Extract of Achillea millefolium on In Vitro Fertilization (IVF) and Embryonic Development Process in Mice
| Autor: | Neda Asliranifam, Shapour Hasanzadeh, Golam Reza Najafi Tazekand |
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| Jazyk: | perština |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, Vol 10, Iss 11, Pp 25-33 (2017) |
| Druh dokumentu: | article |
| ISSN: | 1735-7799 2008-1375 |
| Popis: | Background and Objectives: Achillea millefolium Inflorescences (AMI) is one of the oldest and most well-known medicinal plants with potential antioxidant properties. This study aimed to investigate the effects of three different doses of hydroalcoholic extract of AMI on in vitro fertilization and embryonic development process in mice. Methods: Twenty-four male white laboratory NMRI mice were randomly divided into 4 groups: Group 1 received normal saline (0.1 ml/kg); group 2, 3, and 4 received hydroalcoholic extract of AMI at doses of 75, 150, and 300mg/kg, respectively. Treatment were continued for 35 days. At the end, the mice were euthanized by cervical dislocation, Cauda Epididymis were used to collect sperms, and rate of in vitro fertilization and embryonic development were examined in all groups. Data analysis was performed using one-way ANOVA and Tukey post-hoc tests. Results: In the groups receiving low and medium doses of AMI extract, fertilization rate and the number of blastocysts increased and the number of arrested embryos was reduced, which was not significant compared to the control group. But in the group receiving high dose of the extract, fertilization rate and the number of blastocysts decreased (p |
| Databáze: | Directory of Open Access Journals |
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