| Autor: |
Edward Po-Fan Chu, Candy Hsin-Hua Cho, Wen-Jane Lee, I-Te Lee, I-Fen Cheng, Tzu-Chien Kuo, Ruei-Ying Chen, Wayne Huey-Herng Sheu, Chia-Ning Shen |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Stem Cell Research, Vol 49, Iss , Pp 102109- (2020) |
| Druh dokumentu: |
article |
| ISSN: |
1873-5061 |
| DOI: |
10.1016/j.scr.2020.102109 |
| Popis: |
Retinopathy is a well-known ocular complication that occurs in patients with type 2 diabetes (T2D). Recent evidence also indicates that diabetic patients have an increased prevalence of dry eye syndrome. However, the etiologies of both diabetic retinopathy (DR) and dry eye disease are complex, and their associations with T2D remains to be fully understood. Patient-derived human induced pluripotent stem cells (hiPSCs) enable the generation of disease-specific retinal tissues such as retinal pigment epithelium and lacrimal gland to model disease pathogenesis. Here, we describe the establishment of three hiPSC lines from T2D patients with PDR or dry eye disease. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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