Orthopedic implant-associated infection: the main etiological agents, local resistance and antimicrobial therapy recommendations

Autor: S. A. Bozhkova, R. M. Tikhilov, M. V. Krasnova, A. N. Rukina
Jazyk: ruština
Rok vydání: 2013
Předmět:
Zdroj: Travmatologiâ i Ortopediâ Rossii, Vol 0, Iss 4, Pp 5-15 (2013)
Druh dokumentu: article
ISSN: 2311-2905
2542-0933
DOI: 10.21823/2311-2905-2013--4-5-15
Popis: Surgical site infections remain a major complication of arthroplasty, spinal stabilization or other orthopedic surgeries. The pathogenesis of these complications is related to use orthopedic implants. This retrospective study investigated the microbiological etiology of implant-associated infection after orthopedic surgery over a 3-year period (2010-2012). The antibiotic resistance profiles of 1350 clinical microbial isolates were determined. The biofilm forming capacity of 394 staphylococcal strains was tested. Statistical analysis was performed using Z-criterion. From a results of the microbiological culture, Staphylococcus aureus and Staphylococcus epidermidis were isolated in 49,9% of cases, followed by: Enterococcus faecalis - 6,4%, Pseudomonas aeruginosa - 5,9%, Acinetobacter spp - 5,1% and members of the family Enterobacteriaceae - 4.1%. MRSA amounted to 23,9% and MRSE - 56,6% (p
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