| Autor: |
Emily W.E.M. Phijffer, Joanne G. Wildenbeest, Carole N.M. Brouwer, Matthijs de Hoog, Martin C.J. Kneyber, Sofie Maebe, Anneliese Nusmeier, Maaike A. Riedijk, Roelie M. Wösten-van Asperen, Job B.M. van Woensel, Louis J. Bont, Geert J.W. Frederix |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
The Lancet Regional Health. Europe, Vol 43, Iss , Pp 100965- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2666-7762 |
| DOI: |
10.1016/j.lanepe.2024.100965 |
| Popis: |
Summary: Background: The implementation of the approved respiratory syncytial virus (RSV) preventive interventions in immunisation programmes is advancing rapidly. Insight into healthcare costs of RSV-related paediatric intensive care unit (PICU) admissions is lacking, but of great importance to evaluate the impact of implementation. Therefore, this study aimed to determine the total annual RSV-related paediatric intensive care healthcare costs in the Netherlands. Methods: A nationwide prospective, observational, multicenter study was performed from September 2021 until June 2023. The total annual RSV-related healthcare costs on PICUs in the Netherlands were calculated using RSV-related costs (subgroup I) and consequential costs (subgroup II and III). Subgroup I comprised all PICU admitted infants ≤12 months of age with laboratory-confirmed RSV infection. Subgroup II and III consisted of postponed elective PICU admissions and refused acute PICU admissions due to RSV-related lack of PICU capacity. Findings: A total of 424 infants with RSV-related PICU admission were included. Median age at PICU admission was 46 days (IQR 25–89). The median length of PICU admission was 5 days (IQR 3–8). The total RSV-related PICU costs are € 3,826,386 in 2021–2022, and € 3,183,888 in 2022–2023. Potential costs averted by RSV preventive interventions is € 1.9 to € 2.6 million depending on season, and the duration of protection. Interpretation: RSV-related PICU admissions cost €3.1 to €3.8 million in the Netherlands during one season. The introduction of new RSV preventive interventions into the Dutch immunisation programme will generate significant cost-savings on PICUs and decreases the admission burden of PICUs. Funding: None. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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