Synthetic Applications of Aziridinium Ions

Autor: Jala Ranjith, Hyun-Joon Ha
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Molecules, Vol 26, Iss 6, p 1774 (2021)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/molecules26061774
Popis: Nonactivated aziridine with an electron-donating group at the ring nitrogen should be activated to an aziridinium ion prior to being converted to cyclic and acyclic nitrogen-containing molecules. This review describes ways to generate aziridinium ions and their utilization for synthetic purposes. Specifically, the intra- and intermolecular formation of aziridinium ions with proper electrophiles are classified, and their regio- and stereoselective transformations with nucleophiles are described on the basis of recent developments.
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