Hormonal contraception alters vaginal microbiota and cytokines in South African adolescents in a randomized trial

Autor: Christina Balle, Iyaloo N. Konstantinus, Shameem Z. Jaumdally, Enock Havyarimana, Katie Lennard, Rachel Esra, Shaun L. Barnabas, Anna-Ursula Happel, Zoe Moodie, Katherine Gill, Tanya Pidwell, Ulas Karaoz, Eoin Brodie, Venessa Maseko, Hoyam Gamieldien, Steven E. Bosinger, Landon Myer, Linda-Gail Bekker, Jo-Ann S. Passmore, Heather B. Jaspan
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-020-19382-9
Popis: Hormonal contraception may alter women’s susceptibility to HIV. Here, the authors report the results of a randomized clinical trial substudy assessing the effects of injectable Net-En, oral contraceptives (COC) and Nuvaring on vaginal microbiota and cytokines, associating COC with lower microbial diversity and Nuvaring with increased inflammation.
Databáze: Directory of Open Access Journals