Research progress on the relationship between traumatic brain injury and brain‐gut‐microbial axis

Autor:	Jie Yu, Yun‐Xin Chen, Jin‐Wei Wang, Hai‐Tao Wu
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	brain‐gut‐microbial axis fecal microbiota transplantations microbes nervous system traumatic brain injury Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Zdroj:	Ibrain, Vol 10, Iss 4, Pp 477-487 (2024)
Druh dokumentu:	article
ISSN:	2769-2795 2313-1934
DOI:	10.1002/ibra.12153
Popis:	Abstract Traumatic brain injury (TBI) is a common disease with a high rate of death and disability, which poses a serious threat to human health; thus, the effective treatment of TBI has been a high priority. The brain‐gut‐microbial (BGM) axis, as a bidirectional communication network for information exchange between the brain and gut, plays a crucial role in neurological diseases. This article comprehensively explores the interrelationship between the BGM axis and TBI, including its physiological effects, basic pathophysiology, and potential therapeutic strategies. It highlights how the bidirectional regulatory pathways of the BGM axis could provide new insights into clinical TBI treatment and underscores the necessity for advanced research and development of innovative clinical treatments for TBI.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/dea3cfeba645423fb0abd0757c28a472 Zobrazit plný text záznamu Plný text View record in DOAJ