Potentially severe drug–drug interactions among older people and associations in assisted living facilities in Finland: a cross-sectional study

Autor: Mariko Teramura-Grönblad, Minna Raivio, Niina Savikko, Seija Muurinen, Helena Soini, Merja Suominen, Kaisu Pitkälä
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Scandinavian Journal of Primary Health Care, Vol 34, Iss 3, Pp 250-257 (2016)
Druh dokumentu: article
ISSN: 0281-3432
1502-7724
02813432
DOI: 10.1080/02813432.2016.1207142
Popis: Objective: This study aims to assess potentially severe class D drug–drug interactions (DDDIs) in residents 65 years or older in assisted living facilities with the use of a Swedish and Finnish drug–drug interaction database (SFINX). Design: A cross-sectional study of residents in assisted living facilities in Helsinki, Finland. Setting: A total of 1327 residents were assessed in this study. Drugs were classified according to the Anatomical Therapeutic Chemical (ATC) classification system and DDDIs were coded according to the SFINX. Main outcome measures: Prevalence of DDDIs, associated factors and 3-year mortality among residents. Results: Of the participants (mean age was 82.7 years, 78.3% were females), 5.9% (N = 78) are at risk for DDDIs, with a total of 86 interactions. Participants with DDDIs had been prescribed a higher number of drugs (10.8 (SD 3.8) vs. 7.9 (SD 3.7), p
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