The evaluation of the serum brain natriuretic peptide concentrations in preeclamptic and healthy pregnant women and its potential relationship with mean arterial blood pressure

Autor: Yücedağ, Mehtap, Yılmaz, Özgür, Kırteke, Kenan, Özün Özbay, Pelin, Küme, Tuncay
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Perinatal Journal, Vol 28, Iss 2, Pp 57-61 (2020)
Druh dokumentu: article
ISSN: 1305-3124
DOI: 10.2399/prn.20.0282001
Popis: Objective In this study, we aimed to investigate the correlation between serum brain natriuretic peptide (BNP) concentrations and blood pressure levels by comparing serum brain natriuretic peptide (BNP) concentrations in preeclamptic and normotensive pregnant women and to assess its potential role in the preeclampsia pathogenesis. Methods A total of 48 preeclamptic and 39 normotensive patients were included in the study prospectively. Systolic diastolic and mean arterial blood pressure of the pregnant women were measured. Serum BNP concentrations were measured by enzyme immunoassay method. The variable differences between the groups were analyzed by independent samples t-test. Potential correlations between the variables were assessed by Pearson’s correlation analysis. Results There was no difference between the groups in terms of age (26.18±11.49 years vs. 26.04±14.06 years), gestational age (31.59± 6.94 weeks vs. 30.17±5.72 weeks), parity (2.62±1.4 vs. 2.53±1.82) and body mass index (30.71±16.33 kg/m2 vs. 30.09±13.82 kg/m2) (p>0.05). Systolic (148.66± 61.82 mmHg vs. 126.44±97.47 mmHg; p=0.015), diastolic (81.19±52.25 mmHg vs. 97.29±14.27 mmHg; p=0.019) and mean arterial pressure (113.97±41.76 mmHg vs. 96.26±27.25 mmHg; p
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