Endoscopic versus Laparoscopic Full-Thickness Biopsy in the Pathological Evaluation of the Enteric Nervous System

Autor:	Bodil Ohlsson, Rita J. Gustafsson, Ervin Toth, Bèla Veress, Henrik Thorlacius
Jazyk:	angličtina
Rok vydání:	2018
Předmět:	Enteric dysmotility Enteric neuropathy Full-thickness biopsy Gastrointestinal symptoms Diseases of the digestive system. Gastroenterology RC799-869
Zdroj:	Case Reports in Gastroenterology, Vol 12, Iss 1, Pp 32-40 (2018)
Druh dokumentu:	article
ISSN:	1662-0631
DOI:	10.1159/000486390
Popis:	A full-thickness biopsy of the bowel wall is required to evaluate the enteric nervous system. A patient with aggravating gastrointestinal symptoms underwent a laparoscopic full-thickness biopsy of the ileum and, 1 year later, an endoscopic full-thickness biopsy of the sigmoid colon. Both samples showed enteric neuropathy characterized by vacuolated and enlarged neurons. The length of the myenteric plexus was greater in the endoscopic (23 mm) compared to the laparoscopic (11 mm) biopsy, with fewer tissue artefacts in the laparoscopic approach. Clinical deterioration was paralleled by enteric neuropathy with an increase in the percentage of vacuolated and enlarged enteric neurons from 24 to 35%.
Databáze:	Directory of Open Access Journals
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