COVID-19 reinfection: the role of natural immunity, vaccines, and variants

Autor: Bao Y. Sciscent, Caroline D. Eisele, Lisa Ho, Steven D. King, Rohit Jain, Reshma R. Golamari
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Community Hospital Internal Medicine Perspectives, Vol 11, Iss 6, Pp 733-739 (2021)
Druh dokumentu: article
ISSN: 2000-9666
20009666
DOI: 10.1080/20009666.2021.1974665
Popis: The COVID-19 pandemic has altered innumerable lives. Although recent mass vaccinations offer a glimmer of hope, the rising death toll and new variants continue to dominate the current scenario. As we begin to understand more about SARS-CoV-2 infections, the territory of reinfections with COVID-19 remains unexplored. In this review, we will discuss several aspects of reinfection: (a) How is COVID-19 reinfection characterized? (b) Does prior literature differentiate between reinfection and reactivation? (c) What SARS-CoV-2 strains do the vaccines target and can they protect against new strains? Larger and longer timeline studies are needed to understand reinfection risks. With the ongoing distribution of the SARS-CoV-2 vaccines to provide protection, the understanding of the possibility for SARS-CoV-2 reinfection remains critical. Abbreviations CDC: Centers for Disease ControlSARS-CoV-2: Severe acute respiratory syndrome coronavirus 2COVID-19: Coronavirus disease 2019RT-PCR: Reverse Transcription Polymerase Chain ReactionPASC: Post-Acute Sequelae of SARS-CoV-2 infection
Databáze: Directory of Open Access Journals
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