Development of new levodopa treatment strategies in Parkinson’s disease—from bedside to bench to bedside

Autor:	Sten-Magnus Aquilonius, Dag Nyholm
Jazyk:	angličtina
Rok vydání:	2017
Předmět:	Carbidopa drug development intestinal gel levodopa microtablets Parkinson’s disease Medicine
Zdroj:	Upsala Journal of Medical Sciences, Vol 122, Iss 2, Pp 71-77 (2017)
Druh dokumentu:	article
ISSN:	0300-9734 2000-1967 03009734
DOI:	10.1080/03009734.2017.1285374
Popis:	This review will illustrate the process of moving from an idea through preclinical research and Galenic developments into clinical investigations and finally to approval by regulatory agencies within the European Union. The two new treatment strategies described, levodopa/carbidopa intestinal gel and levodopa/carbidopa microtablets, for advanced Parkinson’s disease, have been developed in collaborative research within departments at Uppsala University. With this historical approach, reference priority is given to reports considered to be of special importance for this more than two decades long process ‘from bedside to bench to bedside’.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/3cdbad13391d4ad9913524bb6298cfd3 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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