M-index as a predictor of glycemia normalization in T2D patients early after bariatric surgery
| Autor: | E. A. Shestakova, I. A. Sklyanik, A. S. Panevina, A. V. Yurasov, Yu. I. Yashkov, M. S. Sineokaya, A. O. Gavrilova, V. V. Evdoshenko, V. V. Fedenko, N. S. Bordan, M. V. Shestakova |
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| Jazyk: | English<br />Russian |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Сахарный диабет, Vol 26, Iss 5, Pp 446-454 (2023) |
| Druh dokumentu: | article |
| ISSN: | 2072-0351 2072-0378 |
| DOI: | 10.14341/DM13045 |
| Popis: | There are several models for predicting remission of type 2 diabetes mellitus (T2D) a year after bariatric surgery — DiaRem, ABSD, IMS, etc. However, these models cannot be used to predict the early normalization of glycemia (within a few months after surgery). These models also do not include the assessment of insulin resistance (IR).AIM. To assess the effect of insulin resistance on the development of remission of T2D after bariatric surgery.METHODS: The study included 42 patients with T2D and severe obesity, who underwent bariatric surgery. Baseline assessment included hyperinsulinemic euglycemic clamp test (with the determination of the M-index (mg/kg/min), and evaluation of HOMA-IR index. Glycemia normalization was determined by self-monitoring ( 1.876 mg/kg/min can be used to predict the glycemia normalization early after bariatric surgery. |
| Databáze: | Directory of Open Access Journals |
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