ROBOTIC PANCREATICODUODENECTOMY FOR THE TREATMENT OF A MIXED NEUROENDOCRINE-NON-NEUROENDOCRINE NEOPLASM (MINEN) OF THE AMPULLA OF VATER

Autor: Rodrigo Cañada Trofo SURJAN, Jorge Francisco de Assis PAULINO, Henrique Perobelli SCHLEINSTEIN, Felipe Moraes Toledo PEREIRA, Estela Regina Ramos FIGUEIRA, José Celso ARDENGH
Jazyk: English<br />Portuguese
Rok vydání: 2024
Předmět:
Zdroj: ABCD: Arquivos Brasileiros de Cirurgia Digestiva, Vol 37 (2024)
Druh dokumentu: article
ISSN: 0102-6720
76817083
DOI: 10.1590/0102-6720202400046e1840
Popis: ABSTRACT Mixed neuroendocrine-non-neuroendocrine tumors (MiNEN) are a rare type of tumor formed by two components, a non-neuroendocrine component that is most often an adenocarcinoma and a neuroendocrine tumor, and each of these components must represent at least 30% of the tumor. The origin of this tumor on the ampulla of Vater or periampullary region is more infrequent. Usually, the lesions are highly aggressive and quickly metastasizing, and their biological behavior is dictated by the high grade of the neuroendocrine component. This is the first report of a patient with ampullary MiNEN treated employing a robotic pancreaticoduodenectomy. Although being submitted to aggressive treatment with complete surgical resection followed by systemic therapy, the patient developed early recurrence with hepatic metastatic disease, demonstrating the hostile nature of these tumors.
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