| Autor: |
Fabien Taieb, Tram Tran Hong, Hien Thi Ho, Binh Nguyen Thanh, Tram Pham Phuong, Dung Viet Ta, Nhung Le Thi Hong, Hien Ba Pham, Lan Thi Huong Nguyen, Huong Thi Nguyen, Thu Trang Nguyen, Edouard Tuaillon, Eric Delaporte, Huong Le Thi, Hau Tran Thi Bich, Tuan Anh Nguyen, Yoann Madec |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
PLoS ONE, Vol 13, Iss 2, p e0191920 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
1932-6203 |
| DOI: |
10.1371/journal.pone.0191920 |
| Popis: |
Viral load (VL) monitoring of HIV-infected patients in decentralized areas is limited due to logistic constraints. Dried Blood Spots (DBS) offer the opportunity to collect samples in remote area which can be easily transferred and tested at a central laboratory. The MOVIDA (Monitoring Of Viral load In Decentralized Area) project evaluated the performance of VL measurements on DBS using the new CE marked optimized Abbott protocol.HIV-1 infected adults from three outpatient clinics in Hanoi (Vietnam) were enrolled into the study between 1 March and 13 April 2017. VL was measured on DBS using the optimized protocol provided by the manufacturer and compared to plasma VL as reference method on the Abbott m2000rt RealTime HIV-1 platform. Sensitivity was defined as the ability for DBS samples to correctly identify VL failure at the threshold of 1000 copies/mL of plasma, while specificity represented the ability to identify patients with a plasma HIV-RNA VL of |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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