| Autor: |
Shilu Zhao, Mingfang Li, Weizhu Ju, Lingyun Gu, Fengxiang Zhang, Hongwu Chen, Kai Gu, Bing Yang, Minglong Chen |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Indian Pacing and Electrophysiology Journal, Vol 18, Iss 3, Pp 95-99 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
0972-6292 |
| DOI: |
10.1016/j.ipej.2017.11.001 |
| Popis: |
Background: Atrial tissue fibrosis can cause electrical or structural remodeling in patients with atrial fibrillation. Transforming growth factor beta 1(TGF-β1) signaling acts as a central role in fibroblast activation. In this report, we aimed to investigate the relationship between serum level of TGF-β1 and mean left atrial voltage in patients with chronic atrial fibrillation (CAF). Methods: A total of 16 consecutive adult patients with CAF who underwent catheter ablation were enrolled. Blood samples for measurement of TGF-β1 were collected from periphery veins and coronary sinus before pulmonary vein isolation. The measurement was performed with a commercially available ELISA kit. Cardiac indices were measured using echocardiography. The left atrial electroanatomic mapping was performed after pulmonary vein isolation. Results: Serum level of TGF-β1 in peripheral blood was higher than that in coronary sinus (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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