| Autor: |
Ignacio Morales-Cané, María Del Rocío Valverde-León, María Aurora Rodríguez-Borrego |
| Jazyk: |
English<br />Spanish; Castilian<br />Portuguese |
| Předmět: |
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| Zdroj: |
Revista Latino-Americana de Enfermagem, Vol 24, Iss 0 |
| Druh dokumentu: |
article |
| ISSN: |
1518-8345 |
| DOI: |
10.1590/1518-8345.1317.2821 |
| Popis: |
abstract Objective: evaluate the effectiveness of epinephrine used during cardiac arrest and its effect on the survival rates and neurological condition. Method: systematic review of scientific literature with meta-analysis, using a random effects model. The following databases were used to research clinical trials and observational studies: Medline, Embase and Cochrane, from 2005 to 2015. Results: when the Return of Spontaneous Circulation (ROSC) with administration of epinephrine was compared with ROSC without administration, increased rates were found with administration (OR 2.02. 95% CI 1.49 to 2.75; I2 = 95%). Meta-analysis showed an increase in survival to discharge or 30 days after administration of epinephrine (OR 1.23; 95% IC 1.05-1.44; I2=83%). Stratification by shockable and non-shockable rhythms showed an increase in survival for non-shockable rhythm (OR 1.52; 95% IC 1.29-1.78; I2=42%). When compared with delayed administration, the administration of epinephrine within 10 minutes showed an increased survival rate (OR 2.03; 95% IC 1.77-2.32; I2=0%). Conclusion: administration of epinephrine appears to increase the rate of ROSC, but when compared with other therapies, no positive effect was found on survival rates of patients with favorable neurological status. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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