Elevated levels of short-term blood pressure variability: A marker for ascending aortic dilatation in hypertensive patients

Autor: Onur Argan, Eyup Avci, Serdar Bozyel, Tarik Yildirim, Ozgen Safak, Seda Elcim Yildirim, Ahmet Dolapoglu, Halil Lutfi Kisacik
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Clinical and Experimental Hypertension, Vol 43, Iss 4, Pp 311-319 (2021)
Druh dokumentu: article
ISSN: 1064-1963
1525-6006
10641963
DOI: 10.1080/10641963.2021.1871915
Popis: Background: Ascending aortic aneurysms are one of the primary causes of mortality. However, not much is known about the etiologies of aortic aneurysm. Recently, in hypertensive (HT) patients, blood pressure variability (BPV) has been recommended as a remarkable risk factor for adverse cardiovascular outcomes. This study aimed to explore the association between short-term BPV and ascending aortic dilatation (AAD). Methods: In this study, a total of 53 HT patients with AAD (aortic size index [ASI] ≥21 mm/m2) and 126 HT patients with a normal ascending aortic diameter (ASI 12.95 had a sensitivity of 61% and a specificity of 59% (area under the curve, 0.659; 95% CI, 0.562–0.756; P= .01); moreover, daytime SD of SBP > 16.4 had sensitivity of 62% and specificity of 61% (AUC, 0.687; 95% CI, 0.591–0.782; P
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