Prognostic Relevance of Promoter Hypermethylation of Multiple Genes in Breast Cancer Patients

Autor: Gayatri Sharma, Sameer Mirza, Yi-Hsin Yang, Rajinder Parshad, Priya Hazrah, Siddartha Datta Gupta, Ranju Ralhan
Jazyk: angličtina
Rok vydání: 2009
Předmět:
Zdroj: Cellular Oncology, Vol 31, Iss 6, Pp 487-500 (2009)
Druh dokumentu: article
ISSN: 1570-5870
1875-8606
DOI: 10.3233/CLO-2009-0507
Popis: Background: Methylation-mediated suppression of detoxification, DNA repair and tumor suppressor genes has been implicated in cancer development. This study was designed to investigate the impact of concurrent methylation of multiple genes in breast tumors on disease prognosis.
Databáze: Directory of Open Access Journals