Molecular Targets for the Treatment of Juvenile Myelomonocytic Leukemia

Autor:	Xiaoling Liu, Himalee Sabnis, Kevin D. Bunting, Cheng-Kui Qu
Jazyk:	angličtina
Rok vydání:	2012
Předmět:	Diseases of the blood and blood-forming organs RC633-647.5
Zdroj:	Advances in Hematology, Vol 2012 (2012)
Druh dokumentu:	article
ISSN:	1687-9104 1687-9112
DOI:	10.1155/2012/308252
Popis:	Significant advances in our understanding of the genetic defects and the pathogenesis of juvenile myelomonocytic leukemia (JMML) have been achieved in the last several years. The information gathered tremendously helps us in designing molecular targeted therapies for this otherwise fatal disease. Various approaches are being investigated to target defective pathways/molecules in this disease. However, effective therapy is still lacking. Development of specific target-based drugs for JMML remains a big challenge and represents a promising direction in this field.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/a3c807d4cc7147a0ab0d4962d471ff00 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF