Mechanism of Viral Glycoprotein Targeting by Membrane-Associated RING-CH Proteins

Autor: Cheng Man Lun, Abdul A. Waheed, Ahlam Majadly, Nicole Powell, Eric O. Freed
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: mBio, Vol 12, Iss 2 (2021)
Druh dokumentu: article
ISSN: 2150-7511
DOI: 10.1128/mBio.00219-21
Popis: Viral envelope glycoproteins are an important structural component on the surfaces of enveloped viruses that direct virus binding and entry and also serve as targets for the host adaptive immune response. In this study, we investigate the mechanism of action of the MARCH family of cellular proteins that disrupt the trafficking and virion incorporation of viral glycoproteins across several virus families.
Databáze: Directory of Open Access Journals