The effect of kidney function on the urate lowering effect and safety of increasing allopurinol above doses based on creatinine clearance: a post hoc analysis of a randomized controlled trial

Autor:	Lisa K. Stamp, Peter T. Chapman, Murray Barclay, Anne Horne, Christopher Frampton, Paul Tan, Jill Drake, Nicola Dalbeth
Jazyk:	angličtina
Rok vydání:	2017
Předmět:	Allopurinol Chronic kidney disease Gout Serum urate Diseases of the musculoskeletal system RC925-935
Zdroj:	Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-9 (2017)
Druh dokumentu:	article
ISSN:	1478-6362
DOI:	10.1186/s13075-017-1491-x
Popis:	Abstract Background The use of allopurinol in people with chronic kidney disease (CKD) remains one of the most controversial areas in gout management. The aim of this study was to determine the effect of baseline kidney function on safety and efficacy of allopurinol dose escalation to achieve serum urate (SU)
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/3c7805f325954c71900018f63a531238 Zobrazit plný text záznamu Full text from SpringerLink View record in DOAJ