Safety profile of treatment with greenlight versus Thulium Laser for benign prostatic hyperplasia
| Autor: | Davide Campobasso, Antonio Barbieri, Tommaso Bocchialini, Gian Luigi Pozzoli, Francesco Dinale, Francesco Facchini, Marco Serafino Grande, Jean Emmanuel Kwe, Michelangelo Larosa, Giulio Guarino, Davide Mezzogori, Elisa Simonetti, Francesco Ziglioli, Antonio Frattini, Umberto Vittorio Maestroni |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Archivio Italiano di Urologia e Andrologia (2023) |
| Druh dokumentu: | article |
| ISSN: | 1124-3562 2282-4197 |
| DOI: | 10.4081/aiua.2023.11101 |
| Popis: | Objective: The major strengths of surgical treatment of benign prostatic hyperplasia with laser are reduced morbidity compared to endoscopic resec-tion. No studies analysed the different risk of intra/peri-opera-tive events between patients undergoing Thulium and GreenLight procedures. Materials and methods: We retrospectively reviewed 100 con-secutive cases undergoing GreenLight vaporization and Thulium procedures performed during the learning curve of two expert endoscopic surgeons. Pre-operative data, intra and post-opera-tive events at 90 days were analysed. Results: Patients on antiplatelet/anticoagulant therapy were pre-dominant in the Green group (p < 0.0001). Rates of blood trans-fusion (p < 0.0038), use of resectoscope (p < 0.0086), and tran-sient stress urinary incontinence were statistically higher in the Thulium group. On the contrary conversions to TURP (p < 0.023) were more frequent in GreenLight patients. Readmissions were more frequently necessary in GreenLight group (24%) vs. Thulium group (26.6%). The overall complica-tion rate in GreenLight and Thulium groups were 31% and 53%respectively; Clavien 3b complications were 13% in Thulium patients versus 1% in GreenLight patients. Conclusions: GreenLight and Thulium treatments show similar safety profiles. Randomized controlled trial are needed to better clarify the rate of major complications in Thulium group, and the incidence of post-operative storage symptoms in these patients’ populations. |
| Databáze: | Directory of Open Access Journals |
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