Ecological and seasonal variations and other factors associated with clinical malaria in the Central Region of Ghana: A cross-sectional study

Autor: Mavis Puopelle Dakorah, Enoch Aninagyei, Juliana Attoh, David Adedia, Clement Okraku Tettey, Isaac Kyei-Barffour, Desmond Omane Acheampong
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Infection and Public Health, Vol 15, Iss 6, Pp 631-637 (2022)
Druh dokumentu: article
ISSN: 1876-0341
DOI: 10.1016/j.jiph.2022.04.014
Popis: Background: This study investigated malaria transmission under various contrasting settings in the Central Region, a malaria endemic region in Ghana. Methods: This cross-sectional study was carried out in five randomly selected districts in the Central Region of Ghana. Three of the districts were forested, while the rest was coastal. Study participants were selected to coincide with either the regular rainy or dry season. From each study site, hospital attendees were randomly selected with prior consent. Consciously, study participants were selected in both rainy (September and October, 2020) and dry (November and December, 2020) seasons. Clinical data for each patient was checked for clinical malaria suspicion and microscopic confirmation of malaria. Using SPSS Version 24 (Chicago, IL, USA), bivariate analysis was done to determine the association of independent variables (ecological and seasonal variations) with malaria status. When the overall analysis did not yield significant association, further statistical analysis was performed after stratification of variables (into age and gender) to determine whether any or both of them would significantly associate with the dependent variable. Results: Of the 3993 study participants, 62.5% were suspected of malaria whereas 38.2% were confirmed to have clinical falciparum malaria. Data analysis revealed that in both rainy and dry seasons, malaria cases were significantly higher in forested districts ) than coastal districts (x2 = 217.9 vs x2 = 50.9; p
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