| Autor: |
Shilpa Ajit Joshi, Madan Deshpande |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Journal of Clinical Ophthalmology and Research, Vol 4, Iss 3, Pp 163-170 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
2320-3897 |
| DOI: |
10.4103/2320-3897.190792 |
| Popis: |
Background: Loss of immune privilege has important connotations for graft survival, often in clinical scenarios where the other eye is irreversibly blind. This article looks at the state of the evidence-based treatment available for high-risk penetrating keratoplasty (P.K.). Materials and Methods: Review of pathophysiological and immunological mechanisms present was done. Conclusion: Pre-, intra-, and post-operative considerations in P.K. in high-risk situation along with the role of immune-suppression are discussed. Success in high-risk keratoplasty depends on an ongoing effort during as well as life-long after P.K. The role of nonimmunological factors such as glaucoma, reactivation of infection, and unstable ocular surface are important determinants in graft failure. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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