Prostate health index can stratify patients with Prostate Imaging Reporting and Data System score 3 lesions on magnetic resonance imaging to reduce prostate biopsies

Autor: John Shung-Lai Leung, Wai-Kit Ma, Brian Sze-Ho Ho, Stacia Tsun-Tsun Chun, Rong Na, Yongle Zhan, Chi-Yuen Ng, Chi-Ho Ip, Ada Tsui-Lin Ng, Yiu-Chung Lam
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Asian Journal of Andrology, Vol 26, Iss 1, Pp 20-24 (2024)
Druh dokumentu: article
ISSN: 1008-682X
1745-7262
DOI: 10.4103/aja202332
Popis: We aim to evaluate prostate health index as an additional risk-stratification tool in patients with Prostate Imaging Reporting and Data System score 3 lesions on multiparametric magnetic resonance imaging. Men with biochemical or clinical suspicion of having prostate cancer who underwent multiparametric magnetic resonance imaging in two tertiary centers (Queen Mary Hospital and Princess Margaret Hospital, Hong Kong, China) between January 2017 and June 2022 were included. Ultrasound-magnetic resonance imaging fusion biopsies were performed after prostate health index testing. Those who only had Prostate Imaging Reporting and Data System score 3 lesions were further stratified into four prostate health index risk groups and the cancer detection rates were analyzed. Out of the 747 patients, 47.3% had Prostate Imaging Reporting and Data System score 3 lesions only. The detection rate of clinically significant prostate cancer in this group was 15.0%. The cancer detection rates of clinically significant prostate cancer had statistically significant differences: 5.3% in prostate health index
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