Brain Connectivity and Graph Theory Analysis in Alzheimer’s and Parkinson’s Disease: The Contribution of Electrophysiological Techniques

Autor: Francesca Miraglia, Fabrizio Vecchio, Chiara Pappalettera, Lorenzo Nucci, Maria Cotelli, Elda Judica, Florinda Ferreri, Paolo Maria Rossini
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Brain Sciences, Vol 12, Iss 3, p 402 (2022)
Druh dokumentu: article
ISSN: 2076-3425
DOI: 10.3390/brainsci12030402
Popis: In recent years, applications of the network science to electrophysiological data have increased as electrophysiological techniques are not only relatively low cost, largely available on the territory and non-invasive, but also potential tools for large population screening. One of the emergent methods for the study of functional connectivity in electrophysiological recordings is graph theory: it allows to describe the brain through a mathematic model, the graph, and provides a simple representation of a complex system. As Alzheimer’s and Parkinson’s disease are associated with synaptic disruptions and changes in the strength of functional connectivity, they can be well described by functional connectivity analysis computed via graph theory. The aim of the present review is to provide an overview of the most recent applications of the graph theory to electrophysiological data in the two by far most frequent neurodegenerative disorders, Alzheimer’s and Parkinson’s diseases.
Databáze: Directory of Open Access Journals
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