Pamidronato dissódico (APD) no tratamento das metástases ósseas.

Autor: L Costa, C Moreira, E B da Costa
Jazyk: English<br />Portuguese
Rok vydání: 1993
Předmět:
Zdroj: Acta Médica Portuguesa, Vol 6, Iss 2 (1993)
Druh dokumentu: article
ISSN: 0870-399X
1646-0758
DOI: 10.20344/amp.3059
Popis: Diphosphonates are potent inhibitors of bone resorption, they have been evaluated in several clinical trials for bone metastases. We performed a clinical study to evaluate the therapeutic effect of Disodium Pamidronate over pain and radiologic evolution in bone metastases (Breast Cancer and Multiple Myeloma patients). The results regarding the first 10 patients concluded that there is good drug tolerability and significant analgesic activity in 6 patients, with sclerosis of lytic skull lesions in one breast cancer patient.
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