Copy number-dependent DNA methylation of the Pyricularia oryzae MAGGY retrotransposon is triggered by DNA damage

Autor: Ba Van Vu, Quyet Nguyen, Yuki Kondo-Takeoka, Toshiki Murata, Naoki Kadotani, Giang Thi Nguyen, Takayuki Arazoe, Shuichi Ohsato, Hitoshi Nakayashiki
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Druh dokumentu: article
ISSN: 2399-3642
DOI: 10.1038/s42003-021-01836-5
Popis: Ba Van Vu, Quyet Nguyen et al. investigate the mechanism by which transposable elements are targeted for DNA methylation, using the fungus Pyricularia oryzae as a model system. They find that copy number-dependent DNA methylation and thus silencing of the MAGGY retrotransposon requires cooperative action of homologous recombination and RNA silencing machinery.
Databáze: Directory of Open Access Journals
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