Actinotignum schaalii infection: Challenges in diagnosis and treatment

Autor: J.M. Sahuquillo-Arce, P. Suárez-Urquiza, A. Hernández-Cabezas, L. Tofan, R. Chouman-Arcas, M. García-Hita, O. Sabalza-Baztán, A. Sellés-Sánchez, N. Lozano-Rodríguez, J. Martí-Cuñat, J.L. López-Hontangas
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Heliyon, Vol 10, Iss 7, Pp e28589- (2024)
Druh dokumentu: article
ISSN: 2405-8440
DOI: 10.1016/j.heliyon.2024.e28589
Popis: Actinotignum schaalii affects elderly people and is associated with individuals with urological-related predispositions, but can be found in a variety of locations, such as cutaneous, intraabdominal, genitourinary and surgical infections. Disseminated infections occur less frequently and are by and large related to urinary tract colonisation.This pathogen is often neglected due to growth requirements, especially in urinary tract infections. We present 107 Actinotignum schaalii isolated from genitourinary samples (80.4%), from skin and soft tissue infections (13.1%), from bone and deep tissue infection (4.7%) and from blood cultures (1.9%). The automated system Alfred 60/AST was paramount for the isolation of 77.6% of the UTI.All the isolates tested were susceptible to penicillin, ampicillin, linezolid, vancomycin, teicoplanin, rifampicin and tetracycline.In conclusion, we present a large series of Actinotignum schaalii infections. This pathogen is hard to isolate, and is resistant to commonly used empirical antimicrobials.
Databáze: Directory of Open Access Journals