Survival benefits with EPIC in addition to HIPEC for low grade appendiceal neoplasms with pseudomyxoma peritonei: a propensity score matched study

Autor: Hayler Raymond, Lockhart Kathleen, Barat Shoma, Cheng Ernest, Mui Jasmine, Shamavonian Raphael, Ahmadi Nima, Alzahrani Nayef, Liauw Winston, Morris David
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Pleura and Peritoneum, Vol 8, Iss 1, Pp 27-35 (2023)
Druh dokumentu: article
ISSN: 2364-768X
DOI: 10.1515/pp-2022-0205
Popis: Appendiceal cancer is a rare malignancy, occurring in roughly 1.2 per 100,000 per year. Low grade appendiceal neoplasams (LAMN) in particular can lead to pseudomyxoma peritonei (PMP), and respond poorly to systemic chemotherapy. Standard treatment includes cytoreduction surgery (CRS) with addition of heated intraoperative peritoneal chemotherapy (HIPEC). Several centres include early postoperative intraperitoneal chemotherapy (EPIC) however; the literature is mixed on the benefits. We aim to examine the benefits of additional EPIC through a propensity-matched analysis.
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