| Autor: |
Oba Ken-ichi, Shimada Hiroaki, Hashimoto Ryota, Kawase Atsushi, Nakanishi Takeo, Iwaki Masahiro |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Endocrine Regulations, Vol 56, Iss 1, Pp 22-30 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1336-0329 |
| DOI: |
10.2478/enr-2022-0003 |
| Popis: |
Objective. Carbamazepine (CBZ), a widely used antiepileptic drug, is one major cause of the idiosyncratic liver injury along with immune reactions. Conversely, prostaglandin E2 (PGE2) demonstrates a hepatoprotective effect by regulating immune reactions and promoting liver repair in various types of liver injury. However, the amount of hepatic PGE2 during CBZ-induced liver injury remains elusive. In this study, we aimed to evaluate the hepatic PGE2 levels during CBZ-induced liver injury using a mouse model. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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