Autor: |
Francisco Magalhães, Kaline Rocha, Victor Marinho, Jéssica Ribeiro, Thomaz Oliveira, Carla Ayres, Thalys Bento, Francisca Leite, Daya Gupta, Victor Hugo Bastos, Bruna Velasques, Pedro Ribeiro, Marco Orsini, Silmar Teixeira |
Jazyk: |
angličtina |
Rok vydání: |
2018 |
Předmět: |
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Zdroj: |
Journal of Biomedical Science, Vol 25, Iss 1, Pp 1-15 (2018) |
Druh dokumentu: |
article |
ISSN: |
1423-0127 |
DOI: |
10.1186/s12929-018-0428-2 |
Popis: |
Abstract Background Parkinson’s disease is described as resulting from dopaminergic cells progressive degeneration, specifically in the substantia nigra pars compacta that influence the voluntary movements control, decision making and time perception. Aim This review had a goal to update the relation between time perception and Parkinson’s Disease. Methodology We used the PRISMA methodology for this investigation built guided for subjects dopaminergic dysfunction in the time judgment, pharmacological models with levodopa and new studies on the time perception in Parkinson’s Disease. We researched on databases Scielo, Pubmed / Medline and ISI Web of Knowledge on August 2017 and repeated in September 2017 and February 2018 using terms and associations relevant for obtaining articles in English about the aspects neurobiology incorporated in time perception. No publication status or restriction of publication date was imposed, but we used as exclusion criteria: dissertations, book reviews, conferences or editorial work. Results/Discussion We have demonstrated that the time cognitive processes are underlying to performance in cognitive tasks and that many are the brain areas and functions involved and the modulators in the time perception performance. Conclusions The influence of dopaminergic on Parkinson’s Disease is an important research tool in Neuroscience while allowing for the search for clarifications regarding behavioral phenotypes of Parkinson’s disease patients and to study the areas of the brain that are involved in the dopaminergic circuit and their integration with the time perception mechanisms. |
Databáze: |
Directory of Open Access Journals |
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