Prediction of biomarkers and therapeutic combinations for anti-PD-1 immunotherapy using the global gene network association
| Autor: | Chia-Chin Wu, Y. Alan Wang, J. Andrew Livingston, Jianhua Zhang, P. Andrew Futreal |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2041-1723 02456486 |
| DOI: | 10.1038/s41467-021-27651-4 |
| Popis: | A lot of cancer patients are not responsive to anti-PD1 therapy. Here, the authors develop a network approach to identify genes, pathways and potential therapeutic combinations and develop an MHC-I gene immunoscore associated with tumour response to anti-PD1. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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