Interleukin-6 and insulin-like growth factor-1 synergistically promote the progression of NSCLC
Autor: | Hexiao Tang, Yuquan Bai, Gaofeng Pan, Xianguo Wang, Yanhong Wei, Zetian Yang, Jinping Zhao |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: | |
Zdroj: | Autoimmunity, Vol 51, Iss 8, Pp 399-407 (2018) |
Druh dokumentu: | article |
ISSN: | 0891-6934 1607-842X 08916934 |
DOI: | 10.1080/08916934.2018.1550079 |
Popis: | The signaling pathways of interleukin-6 (IL-6) and insulin-like growth factor 1 (IGF-1) play an important role in the progression of lung cancer, and this study aimed to explore whether they can synergistically promote the progression of non-small cell lung cancer (NSCLC). We found that IL-6, glycoprotein 130 (GP130), IGF-1 and IGF-1R were highly expressed in NSCLC (p = .000), and there was the correlation between GP130, IGF-1, and IGF-1R (p |
Databáze: | Directory of Open Access Journals |
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