Interleukin-6 and insulin-like growth factor-1 synergistically promote the progression of NSCLC

Autor: Hexiao Tang, Yuquan Bai, Gaofeng Pan, Xianguo Wang, Yanhong Wei, Zetian Yang, Jinping Zhao
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Autoimmunity, Vol 51, Iss 8, Pp 399-407 (2018)
Druh dokumentu: article
ISSN: 0891-6934
1607-842X
08916934
DOI: 10.1080/08916934.2018.1550079
Popis: The signaling pathways of interleukin-6 (IL-6) and insulin-like growth factor 1 (IGF-1) play an important role in the progression of lung cancer, and this study aimed to explore whether they can synergistically promote the progression of non-small cell lung cancer (NSCLC). We found that IL-6, glycoprotein 130 (GP130), IGF-1 and IGF-1R were highly expressed in NSCLC (p = .000), and there was the correlation between GP130, IGF-1, and IGF-1R (p
Databáze: Directory of Open Access Journals
Nepřihlášeným uživatelům se plný text nezobrazuje