Beyond Self-Resistance: ABCF ATPase LmrC Is a Signal-Transducing Component of an Antibiotic-Driven Signaling Cascade Accelerating the Onset of Lincomycin Biosynthesis

Autor: Marketa Koberska, Ludmila Vesela, Vladimir Vimberg, Jakub Lenart, Jana Vesela, Zdenek Kamenik, Jiri Janata, Gabriela Balikova Novotna
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: mBio, Vol 12, Iss 5 (2021)
Druh dokumentu: article
ISSN: 2150-7511
DOI: 10.1128/mBio.01731-21
Popis: Resistance proteins are perceived as mechanisms protecting bacteria from the inhibitory effect of their produced antibiotics or antibiotics from competitors. Here, we report that antibiotic resistance proteins regulate lincomycin biosynthesis in response to subinhibitory concentrations of antibiotics.
Databáze: Directory of Open Access Journals