OPPORTUNITIES TO OPTIMIZE ANTIEPILEPTIC THERAPY WITH USE OF PHARMACOGENETIC BIOMARKERS

Autor:	T. V. Dokukina, M. V. Makhrov, I. V. Gaidukevich, A. A. Gilep, T. S. Golubeva, F. P. Khlebokazov, N. N. Misyuk, P. P. Korolevich
Jazyk:	ruština
Rok vydání:	2016
Předmět:	pharmacogenetics anticonvulsants epilepsy drug-resistance dna genotyping Neurology. Diseases of the nervous system RC346-429
Zdroj:	Эпилепсия и пароксизмальные состояния, Vol 7, Iss 4, Pp 22-28 (2016)
Druh dokumentu:	article
ISSN:	2077-8333 2311-4088
Popis:	Pharmacogenetics allows to determine the cause of the ineffectiveness of drug therapy for certain groups of people who do not respond to treatment or exhibiting an inadequate response to a standard dose of the drug. Pharmacogenetic test can predict the speed and features of a metabolism of antiepileptic drugs in patients with epilepsy, depending on the activity involved in their metabolism enzyme systems and conveyors, that allows to individualize drug therapy in epileptological practice, to avoid side effects.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/e3bc7a4e3b944c48bfdeefe3bf7a5293 Zobrazit plný text záznamu View record in DOAJ